Serum Retinol-Binding Protein 4 (RBP4) and retinol in a cohort of borderline obese women with and without gestational diabetes
نویسندگان
چکیده
منابع مشابه
Liver retinol transporter and receptor for serum retinol-binding protein (RBP4).
Vitamin A (retinol) is absorbed in the small intestine, stored in liver, and secreted into circulation bound to serum retinol-binding protein (RBP4). Circulating retinol may be taken up by extrahepatic tissues or recycled back to liver multiple times before it is finally metabolized or degraded. Liver exhibits high affinity binding sites for RBP4, but specific receptors have not been identified...
متن کاملassociation of plasma retinol binding protein-4 (rbp4) and sonographic grading of fatty liver in obese iranian children
results rbp4 levels in obese children (19 482.9 ± 3 302.2 pg/ml) were higher than those found in the lean control group (14 295.68 ± 2 381.3 pg/ml) (p < 0.05). in the obese patients, rbp4 levels showed a significant correlation with the grade of fatty liver and bmi (p < 0.05). conclusions it was found that the level of rbp4 had a strong correlation with the severity of fatty liver. therefore, r...
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BACKGROUND Retinol-binding protein-4 (RBP4) is a novel adipokine able to modulate the action of insulin in several tissues. A variable degree of insulin resistance characterizes the vast majority of hypertensive (HYP) patients. The aim of this study was to evaluate the relationship between RBP4 and essential hypertension, exploring potential links between RBP4 and other adipokines with some pro...
متن کاملCOMPARISON OF THE EFFECTS OF EIGHT WEEKS OF RESISTANCE TRAINING WITH AND WITHOUT SAFFRON EXTRACT, BARBERRY ON SERUM LEVEL 4 OF RETINOL BINDING PROTEIN, AND INSULIN RESISTANCE IN OBESE MICE WITH HIGH-FAT DIET
Background: The purpose of this study was to compare the effect of eight weeks of resistance training with and without the use of aqueous extracts of barberry and saffron on serum levels of RBP4, glucose, insulin and insulin resistance in obese mice. Methods: In this study, 80 mice with a mean weight of 41± 2 g were exposed to high fat diet for 10 weeks. Then, they were randomly assigned to 8 ...
متن کاملSerum level and polymorphisms of retinol-binding protein-4 and risk for gestational diabetes mellitus: a meta-analysis.
BACKGROUND Retinol-binding protein-4 (RBP4) has been reported to be potentially involved in the pathogenesis of gestational diabetes mellitus (GDM); however, the findings are inconsistent. Our aims were to review the studies that investigated the association of serum levels and polymorphisms of RBP4 with GDM risk, and to provide recommendations for future research. METHODS The databases PubMe...
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ژورنال
عنوان ژورنال: Clinical Biochemistry
سال: 2010
ISSN: 0009-9120
DOI: 10.1016/j.clinbiochem.2009.10.013